The city of Boston, Massachusetts is founded.
In San Francisco, Joshua A. Norton declares himself Norton I, Emperor of the United States and Protector of Mexico.
Battle of Antietam bloodiest day of the American Civil War.
Poet/physician William Carlos Williams (Paterson) born in Rutherford, New Jersey.
Short story writer, novelist, and poet Frank O'Connor (The Stories of Frank O'Connor) born in Cork, Ireland.
Lieutenant Thomas Selfridge becomes the first airplane fatality.
He was a passenger aboard the Wright Flyer, flown by Orville Wright, which crashed after a propellor failure in Fort Myer, Virginia.
German flying ace Manfred von Richthofen (The Red Baron), wins his first aerial combat near Cambrai, France.
Country singer-songwriter Hank Williams (I'm So Lonesome I Could Cry) born in Butler County, Alabama.
Artist Frida Kahlo is in a serious bus accident on her way home from school.
She spends a considerable time in bed where she take up painting to pass the time.
Author Ken Kesey (One Flew Over the Cuckoo's Nest) born in La Junta, Colorado.
Poet Carl Dennis born in St. Louis, Missouri.
Editorial cartoonist Jeff MacNelly born in New York City.
William Golding's first novel, The Lord of the Flies, published.
The Fugitive premiered on ABC-TV.
The XXIV Summer Olympics begin in Seoul, South Korea.